Development of Therapies for Celiac Disease  March 20-21, 2014 

Host Celiac Disease Center at Columbia University, New York
A scientific program designed for those interested in the development of non-dietary therapies for celiac disease. Speakers are listed below.  
Some information was embargoed because of upcoming publication of data.

  • Introduction  Peter Green, MD
    • Immune pathogenesis of celiac disease  Ludwig Sollid - Norway
        Read more by clicking on each section below.
  • The immune response to wheat proteins  Paul Ciclitira - UK (Moderator)
  • Nutritional quality of seed storage proteins Joachim Messing - USA 
  • Wheat gluten and celiac disease - an evolutionary collision  Donald Kasarda – USA
  • Immune response to glutenin and other grains in celiac disease  Paul Ciclitira - UK 
  •  Wheat amylase-trypsin inhibitors: their role in celiac disease and beyond. Detlef Schuppan - Germany 
  • Immune response to non gluten proteins  Armin Alaedini, PhD -- USA 
  • Q&A

  • Celiac disease and refractory celiac disease   Govind Bhagat - USA (Moderator)
  • Neglected intraepithelial innate lymphocytes in celiac disease pathogenesis Govind Bhagat - USA
  • The dark side of the moon : managing refractory celiac disease Joseph Murray - USA
  • Discovery and development of a new anti IL-15 antibody for type II refractory celiac disease therapy Alain Vicari - Switzerland
  • Toleragenic immune modifying nanoparticles for the treatment of celiac disease Daniel Getts - USA

  • Epidemiological factors    Benjamin Lebwohl - USA (Moderator)
  • Unfolding story of celiac disease risk factors Benjamin Lebwohl - USA
  • PreventCD update Maria Luisa Mearin - The Netherlands
  • Results of a prospective study on infant nutrition and risk of celiac disease Carlo Catassi - Italy
  • Pregnancy and child outcomes in celiac disease Jonas Ludvigsson - Sweden
  • Important issues  Markku Maki - Finland (Moderator)
  • Screening in celiac disease in childhood, pros & cons Ivor Hill & Edwin Liu - USA
  • Gluten and biopsy outcome, why is it important in drug trials? Markku Maki - Finland
  • What is the status of the therapies? Joseph A. Murray, MD Mayo Clinic, USA (Moderator)
  • Drug development in celiac disease: FDA perspective Jessica Lee - United States Food & Drug Administration, USA
  • Measuring outcomes in celiac disease Daniel Leffler - USA
  • Glutenase therapy for celiac disease Daniel C. Adelman, MDAlvine Pharmaceuticals, Inc., USA
  • Larazotide : an update Joseph Murray - USA
  • Is a vaccine feasible for celiac disease?  Robert P. Anderson, BMedSc, MBChB, PhDImmusanT, Inc., USA
  • BL-7010 A therapy for celiac disease Yotam Nisemblat - Israel
  • Montelukast in celiac disease Sonia Kupfer - USA
  •  Development of tissue transglutaminase inhibitors Thomas DiRaimondo - USA
  • What is the status of the therapies?    Katri Kaukinen - Finland (Moderator)
  • Probiotics, do they have any role of celiac disease management?  Julio Bai - Argentina
  • Elafin, what is its role in celiac disease  Elena Verdu - Canada
  • Glutenase therapy (DSM)  Chris Mulder - The Netherlands
  • Gluten detection in the food chain  Jennifer Sealey-Voyksner - USA
  • The development of a gluten-degrading enzyme  Ingrid Swanson Pultz - USA
  • Neuropsychiatric manifestations of celiac disease and gluten sensitivity Armin Alaedini - USA (Moderator)
  • Antibodies to food antigens and serious psychiatric disorders Robert Yolken - USA
  • Gluten ataxia: update on mechanism and prevalence Marios Hadjivassiliou - UK
  • Non-celiac gluten sensitivity   Peter HR Green - USA (Moderator)
  • Gluten sensitivity is common Alessio Fasano - USA
  • Gluten sensitivity is uncommon Peter HR Green - USA
  • Gluten sensitivity, is it real? FODMAPs, etc.  Knut Lundin - Norway


          Daniel C. Adelman, MD Alvine Pharmaceuticals, Inc., USA

Armin Alaedini, PhD Columbia University Medical Center, USA

Robert P. Anderson, BMedSc, MBChB, PhD ImmusanT, Inc., USA

Carolina Arguelles Grande, MD Columbia University Medical Center, USA

Julio C. Bai, MD Hospital de Gastroenterología Dr. Carlos Bonorino Udaondo, Argentina

Govind Bhagat, MD Columbia University Medical Center, USA

Carlo Catassi, MD, MPH Università Politecnica delle Marche, Italy

Edward J. Ciaccio, PhD Columbia University Medical Center, USA

Paul Ciclitira, MD, PhD King's College London, UK

Amy R. DeFelice, MD Columbia University Medical Center, USA

Thomas R. DiRaimondo, PhD Sitari Pharma, Inc., USA

         Alessio Fasano, MD Massachusetts General Hospital, USA

Daniel Getts, MBA, PhD Cour Pharmaceutical Development Co., USA

Peter H.R. Green, MD Columbia University Medical Center, USA

Marios Hadjivassiliou, MD Royal Hallamshire Hospital, UK

Ivor D. Hill, MD, MB Nationwide Children's Hospital, USA

Martin F. Kagnoff, MD University of California San Diego, USA

Donald Kasarda, PhD United States Department of Agriculture, USA

Katri Kaukinen, MD, PhD University of Tampere, Finland

Sonia Kupfer, MD University of Chicago, USA

Benjamin Lebwohl, MD, MS Columbia University Medical Center, USA

Jessica J. Lee, MD, MMSc United States Food and Drug Administration, USA

Daniel A. Leffler, MD, MS Beth Israel Deaconess Medical Center, USA

Suzanne K. Lewis, MD Columbia University Medical Center, USA

Edwin Liu, MD University of Colorado Denver, USA

Jonas F. Ludvigsson, MD, PhD Karolinska Institutet, Sweden

          Knut E.A. Lundin, MD, PhD University of Oslo, Norway

Markku Maki, MD, PhD University of Tampere, Finland

Maria Luisa Mearin, MD Leiden University Medical Centre, The Netherlands

Joachim W. Messing, PhD Rutgers University, USA

Chris J.J. Mulder, MD, PhD VU University Medical Center, The Netherlands

Joseph A. Murray, MD Mayo Clinic, USA

Yotam Nisemblat, MSc, MBA BioLineRx Ltd., Israel

Ingrid Swanson Pultz, PhD University of Washington, USA

Norelle Rizkalla Reilly, MD Columbia University Medical Center, USA

Detlef Schuppan, MD, PhD Mainz University Medical Center, Germany

Jennifer A. Sealey Voyksner, PhD Immunogenics, LLC, USA

Ludvig M. Sollid, MD, PhD Oslo University Hospital, Norway

Reidun B. Stenberg, MD, PhD Orebro Universitet, Sweden

Elena Verdú, MD, PhD McMaster University, Canada

Alain Vicari, DVM, PhD Calypso Biotech SA, Switzerland

Robert H. Yolken, MD The Johns Hopkins University School of Medicine, USA