What Is Celiac Disease?
Celiac disease (CD), also known as celiac sprue or gluten-sensitive enteropathy, is a genetically linked autoimmune disorder that can affect both children and
adults. When people with celiac disease eat certain grain-based products that contain gluten, it sets off an immune response that causes damage to the small
intestine. This, in turn, interferes with the small intestine’s ability to absorb nutrients found in food, leading to malnutrition and a variety of other complications.
“Gluten” is the collective term for the amino acid sequences found in wheat, barley, rye and, to a lesser extent, oats, that trigger the immune response.
Who Has Celiac Disease?
Celiac disease is the most common genetic autoimmune disease in the world. This makes celiac disease more common than lupus, rheumatoid arthritis, multiple
sclerosis, epilepsy, Parkinson’s disease, Crohn’s disease or cystic fibrosis. Celiac disease is estimated to affect at least 1% of the worldwide population. Over 3,000,000
people in the US may have celiac disease, but only 150,000 have been diagnosed.
Celiac disease occurs in:
- 3.9 -12.3% of people with Type 1 Diabetes
- 5 -12% of people with Down syndrome, Turner syndrome and other auto-immune conditions
- 20% of people with collagenous colitis
- 4.5% of first degree relatives of people with Celiac disease
What Is the Impact of Celiac Disease?
The elapsed time from onset of symptoms to celiac disease diagnosis averages 10 years in the US. The Canadian Celiac Health Survey published in 2007
reported the mean delay in diagnosis was 11.7 years.
- Untreated celiac disease increases the risk of cancer 200-300%.
- Untreated celiac disease increases the risk of miscarriage 800-900%.
- 66% of those with celiac disease have osteopenia or osteoporosis.
- 51.4% of those with celiac disease have neurologic disorders
- Healthcare costs per untreated celiac in the US: $5,000 - $12,000 annually.
- Total US healthcare cost for all untreated celiacs: $14.5 - $34.8 billion annually.
What Are the Symptoms of Celiac Disease?
Over 300 signs, symptoms, associated disorders and complications may result from celiac disease. Some common health problems include: